Cell Biology - Division U

Fingerprint The fingerprint is based on mining the text of the scientific documents related to the associated persons. Based on that an index of weighted terms is created, which defines the key subjects of research unit

Neoplasms Medicine & Life Sciences
RNA Interference Medicine & Life Sciences
Porcupines Medicine & Life Sciences
Genes Medicine & Life Sciences
Genome Medicine & Life Sciences
beta Catenin Medicine & Life Sciences
Therapeutics Medicine & Life Sciences
Signal Transduction Medicine & Life Sciences

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Research Output 2004 2017

3 Citations

Blockade to pathological remodeling of infarcted heart tissue using a porcupine antagonist

Moon, J., Zhou, H., Zhang, L. S., Tan, W., Liu, Y., Zhang, S., Morlock, L. K., Bao, X., Palecek, S. P., Feng, J. Q., Williams, N. S., Amatruda, J. F., Olson, E. N., Bassel-Duby, R. & Lum, L. Feb 14 2017 In : Proceedings of the National Academy of Sciences of the United States of America. 114, 7, p. 1649-1654 6 p.

Research output: Research - peer-reviewArticle

Porcupines
Regeneration
Non-Fibrillar Collagens
Wnt Proteins
Acyltransferases
1 Citations

Extra-mitochondrial prosurvival BCL-2 proteins regulate gene transcription by inhibiting the SUFU tumour suppressor

Wu, X., Zhang, L. S., Toombs, J., Kuo, Y. C., Piazza, J. T., Tuladhar, R., Barrett, Q., Fan, C. W., Zhang, X., Walensky, L. D., Kool, M., Cheng, S. Y., Brekken, R., Opferman, J. T., Green, D. R., Moldoveanu, T. & Lum, L. Sep 29 2017 In : Nature Cell Biology. 19, 10, p. 1226-1236 11 p.

Research output: Research - peer-reviewArticle

Neoplasms
Proteins
Mitochondrial Membranes
Growth
DNA-Binding Proteins
1 Citations

Development of a triazole class of highly potent Porcn inhibitors

You, L., Zhang, C., Yarravarapu, N., Morlock, L., Wang, X., Zhang, L., Williams, N. S., Lum, L. & Chen, C. Dec 15 2016 In : Bioorganic and Medicinal Chemistry Letters. 26, 24, p. 5891-5895 5 p.

Research output: Research - peer-reviewArticle

Triazoles
Scaffolds
Porcupines
Wnt Proteins
Acyltransferases