Center for the Genetics of Host Defense

Fingerprint The fingerprint is based on mining the text of the scientific documents related to the associated persons. Based on that an index of weighted terms is created, which defines the key subjects of research unit

Mutation Medicine & Life Sciences
Genes Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Proteins Medicine & Life Sciences
Phenotype Medicine & Life Sciences
Drosophila Medicine & Life Sciences
Isoxazoles Medicine & Life Sciences
B-Lymphocytes Medicine & Life Sciences

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Research Output 2006 2017

2 Citations

Creatine maintains intestinal homeostasis and protects against colitis

Turer, E., McAlpine, W., Wang, K. W., Lu, T., Li, X., Tang, M., Zhan, X., Wang, T., Zhan, X., Bu, C. H., Murray, A. R. & Beutler, B. Feb 14 2017 In : Proceedings of the National Academy of Sciences of the United States of America. 114, 7, p. E1273-E1281

Research output: Research - peer-reviewArticle

Creatine
Colitis
Homeostasis
Dextran Sulfate
Adenosine Triphosphate

HCFC2 is needed for IRF1- and IRF2-dependent Tlr3 transcription and for survival during viral infections

Sun, L. , Jiang, Z. , Acosta-Rodriguez, V. A. , Berger, M. , Du, X. , Choi, J. H. , Wang, J. , Wang, K. W. , Kilaru, G. K. , Mohawk, J. A. , Quan, J. , Scott, L. , Hildebrand, S. , Li, X. , Tang, M. , Zhan, X. , Murray, A. R. , Vine, D. L. , Moresco, E. M. Y. , Takahashi, J. S. & 1 others Beutler, B. Nov 1 2017 In : Journal of Experimental Medicine. 214, 11, p. 3263-3277 15 p.

Research output: Research - peer-reviewArticle

Interferon Regulatory Factor-1
Toll-Like Receptor 3
Virus Diseases
Mutation
Double-Stranded RNA
6 Citations

Human Adaptive Immunity Rescues an Inborn Error of Innate Immunity

Israel, L. , Wang, Y. , Bulek, K. , Della Mina, E. , Zhang, Z. , Pedergnana, V. , Chrabieh, M. , Lemmens, N. A. , Sancho-Shimizu, V. , Descatoire, M. , Lasseau, T. , Israelsson, E. , Lorenzo, L. , Yun, L. , Belkadi, A. , Moran, A. , Weisman, L. E. , Vandenesch, F. , Batteux, F. , Weller, S. & 14 others Levin, M., Herberg, J., Abhyankar, A., Prando, C., Itan, Y., van Wamel, W. J. B., Picard, C., Abel, L., Chaussabel, D., Li, X., Beutler, B., Arkwright, P. D., Casanova, J. L. & Puel, A. Feb 23 2017 In : Cell. 168, 5, p. 789-800.e10

Research output: Research - peer-reviewArticle

Adaptive Immunity
Innate Immunity
lipoteichoic acid
Penetrance
Monoclonal Antibodies