Hamon Center Therapeutic Oncology - Minna Lab

Fingerprint The fingerprint is based on mining the text of the scientific documents related to the associated persons. Based on that an index of weighted terms is created, which defines the key subjects of research unit

Neoplasms Medicine & Life Sciences
Lung Neoplasms Medicine & Life Sciences
Non-Small Cell Lung Carcinoma Medicine & Life Sciences
Genes Medicine & Life Sciences
Cell Line Medicine & Life Sciences
Lung Medicine & Life Sciences
Mutation Medicine & Life Sciences
Epithelial Cells Medicine & Life Sciences

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Research Output 1987 2017

CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells

Kim, J. , Hu, Z. , Cai, L. , Li, K. , Choi, E. , Faubert, B. , Bezwada, D. , Rodriguez-Canales, J. , Villalobos, P. , Lin, Y. F. , Ni, M. , Huffman, K. E. , Girard, L. , Byers, L. A. , Unsal-Kacmaz, K. , Peña, C. G. , Heymach, J. V. , Wauters, E. , Vansteenkiste, J. , Castrillon, D. H. & 6 others Chen, B. P. C., Wistuba, I., Lambrechts, D., Xu, J., Minna, J. D. & Deberardinis, R. J. Jun 1 2017 In : Nature. 546, 7656, p. 168-172 5 p.

Research output: Contribution to journalArticle

Carbamyl Phosphate
Ligases
Lung Neoplasms
DNA
Neoplasms

GLI1 blockade potentiates the antitumor activity of PI3K antagonists in lung squamous cell carcinoma

Kasiri, S., Shao, C., Chen, B., Wilson, A. N., Yenerall, P., Timmons, B. C., Girard, L., Tian, H., Behrens, C., Wistuba, I. I., Gazdar, A. F. & Kim, J. Aug 15 2017 In : Cancer Research. 77, 16, p. 4448-4459 12 p.

Research output: Contribution to journalArticle

Phosphatidylinositol 3-Kinases
Squamous Cell Carcinoma
Lung
Hedgehogs
Inhibition (Psychology)

Identification of proteasomal catalytic subunit PSMA6 as a therapeutic target for lung cancer

Kakumu, T., Sato, M., Goto, D., Kato, T., Yogo, N., Hase, T., Morise, M., Fukui, T., Yokoi, K., Sekido, Y., Girard, L., Minna, J. D., Byers, L. A., Heymach, J. V., Coombes, K. R., Kondo, M. & Hasegawa, Y. Apr 1 2017 In : Cancer Science. 108, 4, p. 732-743 12 p.

Research output: Contribution to journalArticle

Lung Neoplasms
Catalytic Domain
Cell Line
Genes
Proteasome Endopeptidase Complex