Fingerprint The fingerprint is based on mining the text of the scientific documents related to the associated persons. Based on that an index of weighted terms is created, which defines the key subjects of research unit

Mutation Medicine & Life Sciences
B-Lymphocytes Medicine & Life Sciences
Lipopolysaccharides Medicine & Life Sciences
Toll-Like Receptor 4 Medicine & Life Sciences
Inflammasomes Medicine & Life Sciences
Ethylnitrosourea Medicine & Life Sciences
Lymphopenia Medicine & Life Sciences
AMP-Activated Protein Kinases Medicine & Life Sciences

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Research Output 2015 2016

1 Citations

Discovery and Structure-Activity Relationships of the Neoseptins: A New Class of Toll-like Receptor-4 (TLR4) Agonists

Morin, M. D., Wang, Y., Jones, B. T., Su, L., Surakattula, M. M. R. P., Berger, M., Huang, H., Beutler, E. K., Zhang, H., Beutler, B. & Boger, D. L. May 26 2016 In : Journal of Medicinal Chemistry. 59, 10, p. 4812-4830 19 p.

Research output: Contribution to journalArticle

Toll-Like Receptor 4
Structure-Activity Relationship

Inhibiting TLR9 and other UNC93B1-dependent TLRs paradoxically increases accumulation of MYD88L265P plasmablasts in vivo

Wang, J. Q., Beutler, B., Goodnow, C. C. & Horikawa, K. 2016 In : Blood. 128, 12, p. 1604-1608 5 p.

Research output: Contribution to journalArticle

In Vitro Techniques
Cell proliferation
3 Citations

Mutation of Fnip1 is associated with B-cell deficiency, cardiomyopathy, and elevated AMPK activity

Siggs, O. M., Stockenhuber, A., Deobagkar-Lele, M., Bull, K. R., Crockford, T. L., Kingston, B. L., Crawford, G., Anzilotti, C., Steeples, V., Ghaffari, S., Czibik, G., Bellahcene, M., Watkins, H., Ashrafian, H., Davies, B., Woods, A., Carling, D., Yavari, A., Beutler, B. & Cornall, R. J. Jun 28 2016 In : Proceedings of the National Academy of Sciences of the United States of America. 113, 26, p. E3706-E3715

Research output: Contribution to journalArticle

AMP-Activated Protein Kinases