Pharmacology - Corey Lab

Fingerprint The fingerprint is based on mining the text of the scientific documents related to the associated persons. Based on that an index of weighted terms is created, which defines the key subjects of research unit

Peptide Nucleic Acids Medicine & Life Sciences
RNA Medicine & Life Sciences
Oligonucleotides Medicine & Life Sciences
Telomerase Medicine & Life Sciences
RNA Interference Medicine & Life Sciences
Gene Expression Medicine & Life Sciences
DNA Medicine & Life Sciences
Gene expression Chemical Compounds

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Research Output 1995 2018

1 Citations

Activating frataxin expression by single-stranded siRNAs targeting the GAA repeat expansion

Shen, X., Kilikevicius, A., O'Reilly, D., Prakash, T. P., Damha, M. J., Rigo, F. & Corey, D. R., Sep 15 2018, In : Bioorganic and Medicinal Chemistry Letters. 28, 17, p. 2850-2855 6 p.

Research output: Contribution to journalArticle

Antisense Oligonucleotides
Friedreich Ataxia
Inborn Genetic Diseases
Mitochondrial Proteins
RNA
5 Citations

Activation of frataxin protein expression by antisense oligonucleotides targeting the mutant expanded repeat

Li, L., Shen, X., Liu, Z., Norrbom, M., Prakash, T. P., O'Reilly, D., Sharma, V. K., Damha, M. J., Watts, J. K., Rigo, F. & Corey, D. R., Feb 1 2018, In : Nucleic Acid Therapeutics. 28, 1, p. 23-33 11 p.

Research output: Contribution to journalArticle

Antisense Oligonucleotides
Friedreich Ataxia
Chemical activation
Proteins
Chemical modification
28 Citations

Chemistry, mechanism and clinical status of antisense oligonucleotides and duplex RNAs

Shen, X. & Corey, D. R., Feb 28 2018, In : Nucleic Acids Research. 46, 4, p. 1584-1600 17 p.

Research output: Contribution to journalArticle

Antisense Oligonucleotides
RNA
Oligonucleotides
Nucleic Acids
Clinical Trials