Pharmacology - Luo Lab

Fingerprint The fingerprint is based on mining the text of the scientific documents related to the associated persons. Based on that an index of weighted terms is created, which defines the key subjects of research unit

Proteins Medicine & Life Sciences
Anaphase-Promoting Complex-Cyclosome Medicine & Life Sciences
Kinetochores Medicine & Life Sciences
Mitosis Medicine & Life Sciences
Phosphorylation Medicine & Life Sciences
Phosphotransferases Medicine & Life Sciences
Transcription Factors Medicine & Life Sciences
Anaphase Medicine & Life Sciences

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Research Output 2002 2017

Mechanistic insight into TRIP13-catalyzed Mad2 structural transition and spindle checkpoint silencing

Brulotte, M. L., Jeong, B. C., Li, F., Li, B., Yu, E. B., Wu, Q., Brautigam, C. A., Yu, H. & Luo, X. Dec 1 2017 In : Nature Communications. 8, 1, 1956

Research output: Research - peer-reviewArticle

enzyme activity
spindles
catalysis
hydrolysis
enzymes

SAV1 promotes Hippo kinase activation through antagonizing the PP2A phosphatase STRIPAK

Bae, S. J., Ni, L., Osinski, A., Tomchick, D. R., Brautigam, C. A. & Luo, X. Oct 24 2017 In : eLife. 6, e30278

Research output: Research - peer-reviewArticle

Phosphoric Monoester Hydrolases
Phosphotransferases
Chemical activation
Long-Acting Thyroid Stimulator
Homeostasis
15 Citations

Autopalmitoylation of TEAD proteins regulates transcriptional output of the Hippo pathway

Chan, P., Han, X., Zheng, B., Deran, M., Yu, J., Jarugumilli, G. K., Deng, H., Pan, D., Luo, X. & Wu, X. Apr 1 2016 In : Nature Chemical Biology. 12, 4, p. 282-289 8 p.

Research output: Research - peer-reviewArticle

Lipoylation
Protein Domains
Palmitates
Cysteine
Lipids