Pharmacology - Ross Lab

Fingerprint The fingerprint is based on mining the text of the scientific documents related to the associated persons. Based on that an index of weighted terms is created, which defines the key subjects of research unit

GTP-Binding Proteins Medicine & Life Sciences
GTPase-Activating Proteins Medicine & Life Sciences
Receptors, Adrenergic, beta Medicine & Life Sciences
Guanosine Triphosphate Medicine & Life Sciences
Type C Phospholipases Medicine & Life Sciences
GTP Phosphohydrolases Medicine & Life Sciences
RGS Proteins Medicine & Life Sciences
Phospholipase C beta Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 1982 2018

2 Citations

Suppression of RGSz1 function optimizes the actions of opioid analgesics by mechanisms that involve the Wnt/β-catenin pathway

Gaspari, S., Purushothaman, I., Cogliani, V., Sakloth, F., Neve, R. L., Howland, D., Ring, R. H., Ross, E. M., Shen, L. & Zachariou, V., Feb 27 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 9, p. E2085-E2094

Research output: Contribution to journalArticle

GTP-Binding Protein Regulators
beta Catenin
Opioid Analgesics
Morphine
Analgesics

The binding of activated Gq to phospholipase C- exhibits anomalous affinity

Navaratnarajah, P., Gershenson, A. & Ross, E. M., 2017, In : Journal of Biological Chemistry. 292, 40, p. 16787-16801 15 p.

Research output: Contribution to journalArticle

Type C Phospholipases
GTPase-Activating Proteins
Phosphatidylinositols
Protein Isoforms
Gq-G11 GTP-Binding Protein alpha Subunits
6 Citations

Amino acids regulate mTORC1 by an obligate two-step mechanism

Dyachok, J., Earnest, S., Iturraran, E. N., Cobb, M. H. & Ross, E. M., Oct 21 2016, In : Journal of Biological Chemistry. 291, 43, p. 22414-22426 13 p.

Research output: Contribution to journalArticle

Amino Acids
Chemical activation
Aminoacylation
mechanistic target of rapamycin complex 1
Tuberous Sclerosis