Pharmacology - Wilkie Lab

Fingerprint The fingerprint is based on mining the text of the scientific documents related to the associated persons. Based on that an index of weighted terms is created, which defines the key subjects of research unit

RGS Proteins Medicine & Life Sciences
GTP-Binding Protein Regulators Medicine & Life Sciences
GTP-Binding Proteins Medicine & Life Sciences
GTPase-Activating Proteins Medicine & Life Sciences
GTP-Binding Protein alpha Subunits Medicine & Life Sciences
Heterotrimeric GTP-Binding Proteins Medicine & Life Sciences
G-Protein-Coupled Receptors Medicine & Life Sciences
Knockout Mice Medicine & Life Sciences

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Profiles

Research Output 1991 2018

Malnutrition in Pancreatic Ductal Adenocarcinoma (PDA): Dietary Pancreatic Enzymes Improve Short-Term Health but Stimulate Tumor Growth

Zolghadri, Y., Pal Choudhuri, S., Ocal, O., Layeghi-Ghalehsoukhteh, S., Berhe, F., Hale, M. A. & Wilkie, T. M. Mar 1 2018 In : American Journal of Pathology. 188, 3, p. 616-626 11 p.

Research output: Contribution to journalArticle

Malnutrition
Adenocarcinoma
Health
Enzymes
Growth

The curious case of Gαs gain-of-function in neoplasia

Innamorati, G., Wilkie, T. M., Kantheti, H. S., Valenti, M. T., Dalle Carbonare, L., Giacomello, L., Parenti, M., Melisi, D. & Bassi, C. Mar 15 2018 In : BMC Cancer. 18, 1, 293

Research output: Contribution to journalArticle

Polyostotic Fibrous Dysplasia
Mutation
Neoplasms
Phenotype
Poisons
5 Citations

The synthetic diazonamide DZ-2384 has distinct effects on microtubule curvature and dynamics without neurotoxicity

Wieczorek, M. , Tcherkezian, J. , Bernier, C. , Prota, A. E. , Chaaban, S. , Rolland, Y. , Godbout, C. , Hancock, M. A. , Arezzo, J. C. , Ocal, O. , Rocha, C. , Olieric, N. , Hall, A. , Ding, H. , Bramoullé, A. , Annis, M. G. , Zogopoulos, G. , Harran, P. G. , Wilkie, T. M. , Brekken, R. A. & 5 others Siegel, P. M., Steinmetz, M. O., Shore, G. C., Brouhard, G. J. & Roulston, A. Nov 16 2016 In : Science Translational Medicine. 8, 365

Research output: Contribution to journalArticle

Microtubules
Tubulin
Vinca
Vinca Alkaloids
Safety