Pharmacology - Zhang Lab

Fingerprint The fingerprint is based on mining the text of the scientific documents related to the associated persons. Based on that an index of weighted terms is created, which defines the key subjects of research unit

plexin Medicine & Life Sciences
Chemical activation Chemical Compounds
Epidermal Growth Factor Receptor Medicine & Life Sciences
Phosphotransferases Medicine & Life Sciences
GTPase-Activating Proteins Medicine & Life Sciences
Proteins Medicine & Life Sciences
Antiviral Agents Medicine & Life Sciences
Dimerization Medicine & Life Sciences

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Research Output 2007 2017

In vitro assay for the Rap GTPase-activating protein activity of the purified cytoplasmic domain of plexin

Pascoe, H. G., Wang, Y. & Zhang, X. 2017 In : Methods in Molecular Biology. 1493, p. 107-118 12 p.

Research output: Research - peer-reviewArticle

GTPase-Activating Proteins
In Vitro Techniques
plexin
Semaphorins
GTP Phosphohydrolases

Multiple truncated isoforms of MAVS prevent its spontaneous aggregation in antiviral innate immune signalling

Qi, N., Shi, Y., Zhang, R., Zhu, W., Yuan, B., Li, X., Wang, C., Zhang, X. & Hou, F. Jun 13 2017 In : Nature Communications. 8, 15676

Research output: Research - peer-reviewArticle

Prions
Virus Diseases
Antiviral Agents
Protein Isoforms
Nix

Structure analyses reveal a regulated oligomerization mechanism of the PlexinD1/GIPC/myosin VI complex

Shang, G., Brautigam, C. A., Chen, R., Lu, D., Torres-Vázquez, J. & Zhang, X. May 24 2017 In : eLife. 6, e27322

Research output: Research - peer-reviewArticle

Oligomerization
myosin VI
Proteins
Dimers
Conformations