Pharmacology - Zhang Lab

Fingerprint The fingerprint is based on mining the text of the scientific documents related to the associated persons. Based on that an index of weighted terms is created, which defines the key subjects of research unit

GTPase-Activating Proteins Medicine & Life Sciences
Semaphorins Medicine & Life Sciences
Epidermal Growth Factor Receptor Medicine & Life Sciences
Dimerization Medicine & Life Sciences
Tankyrases Medicine & Life Sciences
Phosphotransferases Medicine & Life Sciences
Chemical activation Chemical Compounds
Catalytic Domain Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Profiles

Research Output 2007 2018

Regulation of tankyrase activity by a catalytic domain dimer interface

Fan, C., Yarravarapu, N., Chen, H., Kulak, O., Dasari, P., Herbert, J., Yamaguchi, K., Lum, L. & Zhang, X., Jan 1 2018, (Accepted/In press) In : Biochemical and Biophysical Research Communications.

Research output: Contribution to journalArticle

Tankyrases
Dimers
Catalytic Domain
Adenosine Diphosphate
Oligomerization

Structural analyses of FERM domain-mediated membrane localization of FARP1

Kuo, Y. C., He, X., Coleman, A. J., Chen, Y. J., Dasari, P., Liou, J., Biederer, T. & Zhang, X., Dec 1 2018, In : Scientific reports. 8, 1, 10477.

Research output: Contribution to journalArticle

Zebrafish
Medicago
Membranes
Phospholipids
Membrane Proteins
7 Citations

Extra-mitochondrial prosurvival BCL-2 proteins regulate gene transcription by inhibiting the SUFU tumour suppressor

Wu, X., Zhang, L. S., Toombs, J., Kuo, Y. C., Piazza, J. T., Tuladhar, R., Barrett, Q., Fan, C. W., Zhang, X., Walensky, L. D., Kool, M., Cheng, S. Y., Brekken, R., Opferman, J. T., Green, D. R., Moldoveanu, T. & Lum, L., Sep 29 2017, In : Nature Cell Biology. 19, 10, p. 1226-1236 11 p.

Research output: Contribution to journalArticle

Neoplasms
Proteins
Mitochondrial Membranes
DNA-Binding Proteins
Growth