Physiology - Division T

Fingerprint The fingerprint is based on mining the text of the scientific documents related to the associated persons. Based on that an index of weighted terms is created, which defines the key subjects of research unit

Cystic Fibrosis Transmembrane Conductance Regulator Medicine & Life Sciences
Proteins Medicine & Life Sciences
Mutation Medicine & Life Sciences
Cystic Fibrosis Medicine & Life Sciences
Nucleotides Medicine & Life Sciences
Proteasome Endopeptidase Complex Medicine & Life Sciences
Adenosine Triphosphate Medicine & Life Sciences
ATP-Binding Cassette Transporters Medicine & Life Sciences

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Research Output 1994 2017

Direct binding of the Corrector VX-809 to Human CFTR NBD1: Evidence of an Allosteric coupling between the Binding site and the NBD1:CL4 Interface s

Hudson, R. P., Dawson, J. E., Chong, P. A., Yang, Z., Millen, L., Thomas, P. J., Brouillette, C. G. & Forman-Kay, J. D. Aug 1 2017 In : Molecular Pharmacology. 92, 2, p. 124-135 12 p.

Research output: Contribution to journalArticle

Cystic Fibrosis Transmembrane Conductance Regulator
Binding Sites
Freezing
Nucleotides
Hot Temperature
3 Citations

Characterization of novel small-molecule NRF2 activators: Structural and biochemical validation of stereospecific KEAP1 binding

Huerta, C., Jiang, X., Trevino, I., Bender, C. F., Ferguson, D. A., Probst, B., Swinger, K. K., Stoll, V. S., Thomas, P. J., Dulubova, I., Visnick, M. & Wigley, W. C. Nov 1 2016 In : Biochimica et Biophysica Acta - General Subjects. 1860, 11, p. 2537-2552 16 p.

Research output: Contribution to journalArticle

Antioxidants
Inflammation
Modulators
Cysteine
Ligands

N-alpha-acetyltransferases and regulation of CFTR expression

Vetter, A. J., Karamyshev, A. L., Patrick, A. E., Hudson, H. & Thomas, P. J. May 1 2016 In : PLoS One. 11, 5, e0155430

Research output: Contribution to journalArticle

N-Terminal Acetyltransferases
Cystic Fibrosis Transmembrane Conductance Regulator
cystic fibrosis
4-Aminobutyrate Transaminase
degradation