Physiology - Division T

Fingerprint The fingerprint is based on mining the text of the scientific documents related to the associated persons. Based on that an index of weighted terms is created, which defines the key subjects of research unit

Cystic Fibrosis Transmembrane Conductance Regulator Medicine & Life Sciences
Mutation Medicine & Life Sciences
Proteins Medicine & Life Sciences
Cystic Fibrosis Medicine & Life Sciences
Nucleotides Medicine & Life Sciences
Proteasome Endopeptidase Complex Medicine & Life Sciences
Adenosine Triphosphate Medicine & Life Sciences
ATP-Binding Cassette Transporters Medicine & Life Sciences

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Research Output 1994 2017

17β-Estradiol dysregulates innate immune responses to Pseudomonas aeruginosa respiratory infection and is modulated by estrogen receptor antagonism

Abid, S., Xie, S. K., Bose, M., Shaul, P. W., Terada, L. S., Brody, S. L., Thomas, P. J., Katzenellenbogen, J. A., Kim, S. H., Greenberg, D. E. & Jain, R. 2017 In : Infection and Immunity. 85, 10, e00422-17

Research output: Research - peer-reviewArticle

Innate Immunity
Respiratory Tract Infections
Estrogen Receptors
Pseudomonas aeruginosa
Estradiol
4 Citations

Direct binding of the Corrector VX-809 to Human CFTR NBD1: Evidence of an Allosteric coupling between the Binding site and the NBD1:CL4 Interface s

Hudson, R. P., Dawson, J. E., Chong, P. A., Yang, Z., Millen, L., Thomas, P. J., Brouillette, C. G. & Forman-Kay, J. D. Aug 1 2017 In : Molecular Pharmacology. 92, 2, p. 124-135 12 p.

Research output: Research - peer-reviewArticle

Cystic Fibrosis Transmembrane Conductance Regulator
Binding Sites
lumacaftor
S 10
Freezing
8 Citations

Characterization of novel small-molecule NRF2 activators: Structural and biochemical validation of stereospecific KEAP1 binding

Huerta, C., Jiang, X., Trevino, I., Bender, C. F., Ferguson, D. A., Probst, B., Swinger, K. K., Stoll, V. S., Thomas, P. J., Dulubova, I., Visnick, M. & Wigley, W. C. Nov 1 2016 In : Biochimica et Biophysica Acta - General Subjects. 1860, 11, p. 2537-2552 16 p.

Research output: Research - peer-reviewArticle

Modulators
Antioxidants
Molecules
Inflammation
Cysteine