Bruce A Posner

  • 2417 Citations
  • 21 h-Index
1987 …2018
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  • 4 Similar Profiles
Assays Chemical Compounds
Catalytic Antibodies Medicine & Life Sciences
Cells Chemical Compounds
GTP-Binding Proteins Medicine & Life Sciences
Screening Chemical Compounds
Throughput Chemical Compounds
Non-Small Cell Lung Carcinoma Medicine & Life Sciences
Guanosine Triphosphate Medicine & Life Sciences

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Research Output 1987 2018

  • 2417 Citations
  • 21 h-Index
  • 57 Article
  • 1 Comment/debate
Calcitriol Receptors
Calcitriol
Calcium Channels
Insulin
Glucose
4 Citations

A high throughput screen identifies benzoquinoline compounds as inhibitors of Ebola virus replication

Luthra, P., Liang, J., Pietzsch, C. A., Khadka, S., Edwards, M. R., Wei, S., De, S., Posner, B., Bukreyev, A., Ready, J. M. & Basler, C. F., Feb 1 2018, In : Antiviral Research. 150, p. 193-201 9 p.

Research output: Contribution to journalArticle

Ebolavirus
Virus Replication
Antiviral Agents
RNA Viruses
RNA

Author Correction: Small-molecule TFEB pathway agonists that ameliorate metabolic syndrome in mice and extend C. elegans lifespan (Nature Communications (2017) DOI: 10.1038/s41467-017-02332-3)

Wang, C., Niederstrasser, H., Douglas, P. M., Lin, R., Jaramillo, J., Li, Y., Oswald, N. W., Zhou, A., McMillan, E. A., Mendiratta, S., Wang, Z., Zhao, T., Lin, Z., Luo, M., Huang, G., Brekken, R. A., Posner, B. A., MacMillan, J. B., Gao, J. & White, M. A., Dec 1 2018, In : Nature Communications. 9, 1, 2050.

Research output: Contribution to journalComment/debate

document markup languages
HTML
mice
communication
Communication
6 Citations

Chemistry-First Approach for Nomination of Personalized Treatment in Lung Cancer

McMillan, E. A., Ryu, M. J., Diep, C. H., Mendiratta, S., Clemenceau, J. R., Vaden, R. M., Kim, J. H., Motoyaji, T., Covington, K. R., Peyton, M., Huffman, K., Wu, X., Girard, L., Sung, Y., Chen, P. H., Mallipeddi, P. L., Lee, J. Y., Hanson, J., Voruganti, S., Yu, Y. & 20 othersPark, S., Sudderth, J., DeSevo, C., Muzny, D. M., Doddapaneni, H. V., Gazdar, A., Gibbs, R. A., Hwang, T. H., Heymach, J. V., Wistuba, I., Coombes, K. R., Williams, N. S., Wheeler, D. A., MacMillan, J. B., Deberardinis, R. J., Roth, M. G., Posner, B. A., Minna, J. D., Kim, H. S. & White, M. A., May 3 2018, In : Cell. 173, 4, p. 864-878.e29

Research output: Contribution to journalArticle

Lung Neoplasms
Neoplasms
Oncology
Biosynthesis
Small Molecule Libraries

Discovery of Cytochrome P450 4F11-Activated Inhibitors of Stearoyl Coenzyme A Desaturase

Winterton, S. E., Capota, E., Wang, X., Chen, H., Mallipeddi, P. L., Williams, N. S., Posner, B. A., Nijhawan, D. & Ready, J. M., Jan 12 2018, (Accepted/In press) In : Journal of Medicinal Chemistry.

Research output: Contribution to journalArticle

Stearoyl-CoA Desaturase
Cytochrome P-450 Enzyme System
Unsaturated Fatty Acids
Structure-Activity Relationship
Urea