• 8961 Citations
  • 16 h-Index
19992019
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Fingerprint Fingerprint is based on mining the text of the experts' scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 6 Similar Profiles
G-Protein-Coupled Receptors Medicine & Life Sciences
Adrenergic Receptors Medicine & Life Sciences
Ligands Medicine & Life Sciences
Orexin Receptors Medicine & Life Sciences
Proteins Medicine & Life Sciences
GTP-Binding Proteins Medicine & Life Sciences
Membrane Proteins Medicine & Life Sciences
Labeling Chemical Compounds

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Research Output 1999 2019

  • 8961 Citations
  • 16 h-Index
  • 23 Article
  • 4 Chapter
  • 1 Conference contribution
  • 1 Short survey

Isotopic Labeling of Eukaryotic Membrane Proteins for NMR Studies of Interactions and Dynamics

Dikiy, I., Clark, L. D., Gardner, K. H. & Rosenbaum, D. M., Jan 1 2019, Methods in Enzymology. Wand, A. J. (ed.). Academic Press Inc., p. 37-65 29 p. (Methods in Enzymology; vol. 614).

Research output: Chapter in Book/Report/Conference proceedingChapter

Labeling
Membrane Proteins
Nuclear magnetic resonance
G-Protein-Coupled Receptors
Adenosine A2A Receptors

Crystal structure of the human NK1 tachykinin receptor

Yin, J., Chapman, K., Clark, L. D., Shao, Z., Borek, D., Xu, Q., Wang, J. & Rosenbaum, D. M., Dec 26 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 52, p. 13264-13269 6 p.

Research output: Contribution to journalArticle

Tachykinin Receptors
aprepitant
Substance P
L 760735
Vomiting
3 Citations

Crystal Structures of Human Orexin 2 Receptor Bound to the Subtype-Selective Antagonist EMPA

Suno, R., Kimura, K. T., Nakane, T., Yamashita, K., Wang, J., Fujiwara, T., Yamanaka, Y., Im, D., Horita, S., Tsujimoto, H., Tawaramoto, M. S., Hirokawa, T., Nango, E., Tono, K., Kameshima, T., Hatsui, T., Joti, Y., Yabashi, M., Shimamoto, K., Yamamoto, M. & 4 othersRosenbaum, D. M., Iwata, S., Shimamura, T. & Kobayashi, T., Jan 2 2018, In : Structure. 26, 1, p. 7-19.e5

Research output: Contribution to journalArticle

Orexin Receptors
Synchrotrons
Molecular Dynamics Simulation
Dissociative Disorders
Crystallography
2 Citations

On the use of Pichia pastoris for isotopic labeling of human GPCRs for NMR studies

Clark, L., Dikiy, I., Rosenbaum, D. M. & Gardner, K. H., Aug 1 2018, In : Journal of Biomolecular NMR. 71, 4, p. 203-211 9 p.

Research output: Contribution to journalArticle

Pichia
G-Protein-Coupled Receptors
Labeling
Membrane Proteins
Nuclear magnetic resonance
10 Citations

Ligand modulation of sidechain dynamics in a wild-type human GPCR

Clark, L. D., Dikiy, I., Chapman, K., Rödström, K. E. J., Aramini, J., LeVine, M. V., Khelashvili, G., Rasmussen, S. G. F., Gardner, K. H. & Rosenbaum, D. M., Oct 6 2017, In : eLife. 6, e28505.

Research output: Contribution to journalArticle

Nuclear magnetic resonance
Modulation
Ligands
Adenosine-5'-(N-ethylcarboxamide)
Isoleucine