Find Research Outputs

2018

A missense variant in SLC39A8 is associated with severe idiopathic scoliosis

Haller, G., McCall, K., Jenkitkasemwong, S., Sadler, B., Antunes, L., Nikolov, M., Whittle, J., Upshaw, Z., Shin, J., Baschal, E., Cruchaga, C., Harms, M., Raggio, C., Morcuende, J. A., Giampietro, P., Miller, N. H., Wise, C., Gray, R. S., Solnica-Krezel, L., Knutson, M. & 2 othersDobbs, M. B. & Gurnett, C. A., Dec 1 2018, In : Nature communications. 9, 1, 4171.

Research output: Contribution to journalArticle

Scoliosis
Manganese
mutations
manganese
Plasmas
1 Citations

A multi-ethnic meta-analysis confirms the association of rs6570507 with adolescent idiopathic scoliosis

Japan Scoliosis Clinical Research Group (JSCRG) & Texas Scottish Rite Hospital for Children Clinical Group (TSRHCCG), Dec 1 2018, In : Scientific reports. 8, 1, 11575.

Research output: Contribution to journalArticle

Scoliosis
Meta-Analysis
Genome-Wide Association Study
Far East
Computer Simulation

A multilevel computational characterization of endophenotypes in addiction

Fiore, V. G., Ognibene, D., Adinoff, B. & Gu, X., Jul 1 2018, In : eNeuro. 5, 4, e0151-18.2018.

Research output: Contribution to journalArticle

Endophenotypes
Corpus Striatum
Choice Behavior
Reward
Dopamine

A Multi-Targeted Quality Improvement Project of CT-Guided Procedure Start Times

Collard, M., Wachsmann, J., Thrash, S., Herring, S., Caramucci, M., Hrebec, L., Collins, J. & Kwon, J., Apr 1 2018, (Accepted/In press) In : American Journal of Medical Quality.

Research output: Contribution to journalArticle

Quality Improvement

Amyloid-Beta (1-40) Peptide and Subclinical Cardiovascular Disease

Stamatelopoulos, K., Pol, C. J., Ayers, C., Georgiopoulos, G., Gatsiou, A., Brilakis, E. S., Khera, A., Drosatos, K., de Lemos, J. A. & Stellos, K., Aug 28 2018, In : Journal of the American College of Cardiology. 72, 9, p. 1060-1061 2 p.

Research output: Contribution to journalLetter

Cardiovascular Diseases
Peptides
amyloid beta-protein (1-40)

An additional case of Hennekam lymphangiectasia–lymphedema syndrome caused by loss-of-function mutation in ADAMTS3

Scheuerle, A., Sweed, N. T., Timmons, C. F., Smith, E. D., Alcaraz, W. A. & Shinde, D. N., Jan 1 2018, (Accepted/In press) In : American Journal of Medical Genetics, Part A.

Research output: Contribution to journalArticle

Genetic Databases
Vascular Endothelial Growth Factor C
Disintegrins
Mutation
Nonsense Codon
7 Citations

An Adipose Tissue Atlas: An Image-Guided Identification of Human-like BAT and Beige Depots in Rodents

Zhang, F., Hao, G., Shao, M., Nham, K., An, Y., Wang, Q., Zhu, Y., Kusminski, C. M., Hassan, G., Gupta, R. K., Zhai, Q., Sun, X., Scherer, P. E. & Oz, O. K., Jan 9 2018, In : Cell Metabolism. 27, 1, p. 252-262.e3

Research output: Contribution to journalArticle

Forensic Anthropology
Atlases
Adipose Tissue
Rodentia
Fluorodeoxyglucose F18

An Adolescent with Left Ventricular Noncompaction and Ebstein Anomaly Presenting with Advanced Heart Failure: Discharge from Hospital with a Biventricular Assist Device

Das, B. B., Chrisant, M., Lavandosky, G., Zakrzewski, M., Winchester, R., Turner, I., Bibevski, S. & Scholl, F., Nov 1 2018, In : Journal of Pediatrics. 202, p. 304-310.e1

Research output: Contribution to journalArticle

Ebstein Anomaly
Heart Failure
Equipment and Supplies
1 Citations

An algorithmic approach for the management of ostial right coronary artery chronic total occlusions

Avran, A., Boukhris, M., Drogoul, L. & Brilakis, E. S., Jan 1 2018, (Accepted/In press) In : Catheterization and Cardiovascular Interventions.

Research output: Contribution to journalArticle

Coronary Vessels
Catheters
Punctures
Aorta
Dissection

Analysis of Clinical Factors and Outcomes Associated with Nonuse of Collected Peripheral Blood Stem Cells for Autologous Stem Cell Transplants in Transplant-Eligible Patients with Multiple Myeloma

Kansagra, A., Gonsalves, W. I., Gertz, M. A., Buadi, F. K., Dingli, D., Dispenzieri, A., Lacy, M. Q., Hayman, S. R., Kapoor, P., Muchtar, E., Kourelis, T. V., Warsame, R., Leung, N., Zeldenrust, S. R., Lust, J. A., Rajkumar, S. V., Kyle, R. A., Hogan, W. & Kumar, S. K., Jan 1 2018, (Accepted/In press) In : Biology of Blood and Marrow Transplantation.

Research output: Contribution to journalArticle

Stem Cell Transplantation
Multiple Myeloma
Statistical Factor Analysis
Stem Cells
Transplants

Analysis of femoral version in patients undergoing periacetabular osteotomy for symptomatic acetabular dysplasia

Sankar, W. N., Novais, E., Koueiter, D., Refakis, C., Sink, E., Millis, M. B., Kim, Y. J., Clohisy, J., Wells, J., Nepple, J. & Zaltz, I., Jan 1 2018, In : Journal of the American Academy of Orthopaedic Surgeons. 26, 15, p. 545-551 7 p.

Research output: Contribution to journalArticle

Osteotomy
Thigh
Hip
Articular Range of Motion
Acetabulum
6 Citations

Analysis of PD1, PDL1, PDL2 expression and T cells infiltration in 1014 gastric cancer patients

Xing, X., Guo, J., Wen, X., Ding, G., Li, B., Dong, B., Feng, Q., Li, S., Zhang, J., Cheng, X., Guo, T., Du, H., Hu, Y., Wang, X., Li, L., Li, Q., Xie, M., Li, L., Gao, X., Shan, F. & 5 othersLi, Z., Ying, X., Zhou, T., Wang, J. & Ji, J., Mar 4 2018, In : OncoImmunology. 7, 3, e1356144.

Research output: Contribution to journalArticle

Stomach Neoplasms
T-Lymphocytes
Proliferating Cell Nuclear Antigen
Neoplasms
Epstein-Barr Virus Infections
Craniosynostoses
Head

Anatomy and Surgical Approach of the Ear and Temporal Bone

Isaacson, B., Sep 1 2018, In : Head and Neck Pathology. 12, 3, p. 321-327 7 p.

Research output: Contribution to journalArticle

Temporal Bone
Ear
Anatomy
Neoplastic Processes
Skull Base
Medical Futility
Thrombophilia
Transient Ischemic Attack
Stroke
Diagnostic Errors

An elderly woman who could not stay asleep

Edaki, O., Danish, N. & Khawaja, I. S., Jun 1 2018, In : Psychiatric Annals. 48, 6, p. 306-308 3 p.

Research output: Contribution to journalArticle

1 Citations

An empirical approach leveraging tumorgrafts to dissect the tumor microenvironment in renal cell carcinoma identifies missing link to prognostic inflammatory factors

Wang, T., Lu, R., Kapur, P., Jaiswal, B. S., Hannan, R., Zhang, Z., Pedrosa, I., Luke, J. J., Zhang, H., Goldstein, L. D., Yousuf, Q., Gu, Y. F., McKenzie, T., Joyce, A., Kim, M. S., Wang, X., Luo, D., Onabolu, O., Stevens, C., Xie, Z. & 11 othersChen, M., Filatenkov, A., Torrealba, J., Luo, X., Guo, W., He, J., Stawiski, E., Modrusan, Z., Durinck, S., Seshagiri, S. & Brugarolas, J., Sep 1 2018, In : Cancer Discovery. 8, 9, p. 1142-1155 14 p.

Research output: Contribution to journalArticle

Tumor Microenvironment
Renal Cell Carcinoma
Neoplasms
Inflammation
RNA Sequence Analysis
2 Citations

An Endothelial-to-Adipocyte Extracellular Vesicle Axis Governed by Metabolic State

Crewe, C., Joffin, N., Rutkowski, J. M., Kim, M., Zhang, F., Towler, D. A., Gordillo, R. & Scherer, P. E., Oct 18 2018, In : Cell. 175, 3, p. 695-708.e13

Research output: Contribution to journalArticle

Endothelial cells
Caveolin 1
Adipocytes
Tissue
Cell signaling
2 Citations

Anesthesia and the developing brain: A way forward for laboratory and clinical research

Disma, N., O'Leary, J. D., Loepke, A. W., Brambrink, A. M., Becke, K., Clausen, N. G., De Graaff, J. C., Liu, F., Hansen, T. G., McCann, M. E., Salorio, C. F., Soriano, S., Sun, L. S., Szmuk, P., Warner, D. O., Vutskits, L. & Davidson, A. J., Sep 1 2018, In : Paediatric anaesthesia. 28, 9, p. 758-763 6 p.

Research output: Contribution to journalArticle

Anesthesia
Brain
Research
Anesthetics
Medical Laboratory Science

Anesthesiology, automation, and artificial intelligence

Alexander, J. C. & Joshi, G. P., Jan 1 2018, In : Baylor University Medical Center Proceedings. 31, 1, p. 117-119 3 p.

Research output: Contribution to journalArticle

Anesthesiology
Artificial Intelligence
Automation
Industry
Anesthesia

A neural pathway controlling motivation to exert effort

Proulx, C. D., Aronson, S., Milivojevic, D., Molina, C., Loi, A., Monk, B., Shabel, S. J. & Malinow, R., May 29 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 22, p. 5792-5797 6 p.

Research output: Contribution to journalArticle

Habenula
Neural Pathways
Motivation
Reward
Pleasure

An Evolutionarily Conserved Structural Platform for PRC2 Inhibition by a Class of Ezh2 Inhibitors

Bratkowski, M., Yang, X. & Liu, X., Dec 1 2018, In : Scientific Reports. 8, 1, 9092.

Research output: Contribution to journalArticle

Polycomb Repressive Complex 2
Histone-Lysine N-Methyltransferase
Fungi
Chaetomium
Pharmaceutical Preparations
2 Citations

An evolutionary hotspot defines functional differences between CRYPTOCHROMES

Rosensweig, C., Reynolds, K. A., Gao, P., Laothamatas, I., Shan, Y., Ranganathan, R., Takahashi, J. S. & Green, C. B., Dec 1 2018, In : Nature Communications. 9, 1, 1138.

Research output: Contribution to journalArticle

Circadian Clocks
clocks
Sequence Analysis
Clocks
Mutation

A newborn with hypothermia and hyperammonemia

Nguyen, K. Q. N., Jones, P. M. & Patel, K., Feb 1 2018, In : Clinical Chemistry. 64, 2, p. 411-413 3 p.

Research output: Contribution to journalShort survey

Hyperammonemia
Hypothermia

A new BRB model for security-state assessment of cloud computing based on the impact of external and internal environments

Wei, H., Hu, G. Y., Zhou, Z. J., Qiao, P. L., Zhou, Z. G. & Zhang, Y. M., Mar 1 2018, In : Computers and Security. 73, p. 207-218 12 p.

Research output: Contribution to journalArticle

Cloud computing
assessment basis
Maximum likelihood
expert
event

A new class of agents for estrogen-receptor-positive breast cancer

Ekoue, D. N., Unni, N. & Raj, G. V., Apr 3 2018, In : Expert Review of Clinical Pharmacology. 11, 4, p. 325-328 4 p.

Research output: Contribution to journalEditorial

Estrogen Receptors
Breast Neoplasms
10 Citations

A New Evidential Reasoning-Based Method for Online Safety Assessment of Complex Systems

Zhao, F. J., Zhou, Z. J., Hu, C. H., Chang, L. L., Zhou, Z. G. & Li, G. L., Jun 1 2018, In : IEEE Transactions on Systems, Man, and Cybernetics: Systems. 48, 6, p. 954-966 13 p.

Research output: Contribution to journalArticle

Large scale systems
Dynamical systems
Inertial navigation systems
Electric fuses
Agglomeration

A new left ventricular assist device - Better, but still not ideal

Drazner, M. H., Apr 12 2018, In : New England Journal of Medicine. 378, 15, p. 1442-1443 2 p.

Research output: Contribution to journalEditorial

Heart-Assist Devices

A new look for the growing microtubule end?

Rice, L. M., Aug 1 2018, In : Journal of Cell Biology. 217, 8, p. 2609-2611 3 p.

Research output: Contribution to journalReview article

Microtubules
Electron Microscope Tomography
Three-Dimensional Imaging
In Vitro Techniques

A New Model to Predict Benign Histology in Residual Retroperitoneal Masses After Chemotherapy in Nonseminoma

Leão, R., Nayan, M., Punjani, N., Jewett, M. A. S., Fadaak, K., Garisto, J., Lewin, J., Atenafu, E. G., Sweet, J., Anson-Cartwright, L., Boström, P., Chung, P., Warde, P., Bedard, P. L., Bagrodia, A., Freifeld, Y., Power, N., Winquist, E. & Hamilton, R. J., Jan 1 2018, (Accepted/In press) In : European Urology Focus.

Research output: Contribution to journalArticle

Lymph Node Excision
Histology
Drug Therapy
Testicular Neoplasms
Unnecessary Procedures

A new species of Wahydra from Ecuador (Hesperiidae, Hesperiinae, Anthoptini)

Carneiro, E., Dolibaina, D. R., Grishin, N. V. & Warren, A. D., Mar 8 2018, In : Zootaxa. 4392, 1, p. 196-200 5 p.

Research output: Contribution to journalReview article

Hesperiidae
Ecuador
new species
Andes region
mountain

A New Treatment Strategy for Saphenous Vein Graft Lesions? Letting it Go

Brilakis, E. S., Banerjee, S. & Burke, M. N., May 8 2018, In : Journal of the American College of Cardiology. 71, 18, p. 1983-1985 3 p.

Research output: Contribution to journalEditorial

Saphenous Vein
Transplants

An imaging glimpse into the autistic brain

Rollins, N. K., Jan 1 2018, In : Radiology. 286, 1, p. 227-228 2 p.

Research output: Contribution to journalEditorial

Brain
1 Citations

Animal models in neonatal resuscitation research: What can they teach us?

Hooper, S. B., te Pas, A. B., Polglase, G. R. & Wyckoff, M., Jan 1 2018, (Accepted/In press) In : Seminars in Fetal and Neonatal Medicine.

Research output: Contribution to journalArticle

Resuscitation
Animal Models
Research
Clinical Trials
Evidence-Based Medicine

An increase in LRRK2 suppresses autophagy and enhances dectin-1–induced immunity in a mouse model of colitis

Takagawa, T., Kitani, A., Fuss, I., Levine, B., Brant, S. R., Peter, I., Tajima, M., Nakamura, S. & Strober, W., Jun 6 2018, In : Science Translational Medicine. 10, 444, eaan8162.

Research output: Contribution to journalArticle

Autophagy
Colitis
Dendritic Cells
Immunity
Crohn Disease

An infant’s sudden-onset rash and swelling: Can you identify the cause?

Yuan, Y. Y. E., Nesiama, J. A. & Huang, C., Jun 1 2018, In : Consultant. 58, 6, e184.

Research output: Contribution to journalArticle

Exanthema

An inflammatory transcriptional switch

Murtaugh, L. C. & MacDonald, R. J., Feb 22 2018, In : Nature. 554, 7693, p. 470-472 3 p.

Research output: Contribution to journalShort survey

7 Citations

An interdisciplinary response to contemporary concerns about brain death determination

Lewis, A., Bernat, J. L., Blosser, S., Bonnie, R. J., Epstein, L. G., Hutchins, J., Kirschen, M. P., Rubin, M., Russell, J. A., Sattin, J. A., Wijdicks, E. F. M. & Greer, D. M., Jan 1 2018, In : Neurology. 90, 9, p. 423-426 4 p.

Research output: Contribution to journalArticle

Brain Death
Nervous System
Quality Improvement
Practice Guidelines
Ethics
1 Citations

An international meta-analysis confirms the association of BNC2 with adolescent idiopathic scoliosis

Ogura, Y., Takeda, K., Kou, I., Khanshour, A., Grauers, A., Zhou, H., Liu, G., Fan, Y. H., Zhou, T., Wu, Z., Takahashi, Y., Matsumoto, M., Kawakami, N., Tsuji, T., Uno, K., Suzuki, T., Ito, M., Minami, S., Kotani, T., Sakuma, T. & 55 othersYanagida, H., Taneichi, H., Yonezawa, I., Sudo, H., Chiba, K., Hosogane, N., Nishida, K., Kakutani, K., Akazawa, T., Kaito, T., Watanabe, K., Harimaya, K., Taniguchi, Y., Shigematsu, H., Demura, S., Iida, T., Kono, K., Okada, E., Fujita, N., Yagi, M., Nakamura, M., Karol, L. A., Rathjen, K. E., Sucato, D. J., Birch, J. G., Johnston, C. E., Richards, B. S., Ramo, B., McIntosh, A. L., Herring, J. A., Milbrandt, T. A., Talwakar, V. R., Iwinski, H. J., Muchow, R. D., Tassone, J. C., Liu, X. C., Shindell, R., Schrader, W., Eberson, C., Lapinsky, A., Loder, R., Davey, J., Einarsdottir, E., Kere, J., Huang, D., Qiu, G., Xu, L., Qiu, Y., Wise, C. A., Song, Y. Q., Wu, N., Su, P., Gerdhem, P., Watanabe, K. & Ikegawa, S., Dec 1 2018, In : Scientific Reports. 8, 1, 4730.

Research output: Contribution to journalArticle

Scoliosis
Meta-Analysis
Genome-Wide Association Study
Computer Simulation
Population

An investigation of left–right vocal fold symmetry in rheological and histological properties

Xu, C. C., Gao, A. & Zhang, S., Oct 1 2018, In : Laryngoscope. 128, 10, p. E359-E364

Research output: Contribution to journalArticle

Vocal Cords
Statistical Models
Larynx
Rabbits
Mucous Membrane
1 Citations

An isolated CLASP TOG domain suppresses microtubule catastrophe and promotes rescue

Majumdar, S., Kim, T., Chen, Z., Munyoki, S., Tso, S. C., Brautigam, C. A. & Rice, L. M., Jun 1 2018, In : Molecular Biology of the Cell. 29, 11, p. 1359-1375 17 p.

Research output: Contribution to journalArticle

Microtubules
Tubulin
Proteins
Chromosome Segregation
Point Mutation
1 Citations

Anomalies Characteristic of Central Nervous System Demyelination: Radiologically Isolated Syndrome

RISConsortium, Feb 1 2018, In : Neurologic Clinics. 36, 1, p. 59-68 10 p.

Research output: Contribution to journalReview article

Demyelinating Diseases
Multiple Sclerosis
Central Nervous System
Spinal Cord
White Matter
2 Citations

A noncanonical role for dynamin-1 in regulating early stages of clathrin-mediated endocytosis in non-neuronal cells

Srinivasan, S., Burckhardt, C. J., Bhave, M., Chen, Z., Chen, P. H., Wang, X., Danuser, G. & Schmid, S. L., Apr 18 2018, In : PLoS Biology. 16, 4, e2005377.

Research output: Contribution to journalArticle

Dynamin I
clathrin
Clathrin
endocytosis
Endocytosis

A nonhuman primate model of early Alzheimer's disease pathologic change: Implications for disease pathogenesis

Latimer, C. S., Shively, C. A., Keene, C. D., Jorgensen, M. J., Andrews, R. N., Register, T. C., Montine, T. J., Wilson, A. M., Neth, B. J., Mintz, A., Maldjian, J. A., Whitlow, C. T., Kaplan, J. R. & Craft, S., Jan 1 2018, (Accepted/In press) In : Alzheimer's and Dementia.

Research output: Contribution to journalArticle

Primates
Cerebrospinal Fluid
Alzheimer Disease
Cercopithecus aethiops
Amyloid Plaques

Another way to not get eaten news-and-views

Zhang, C. C. & Fu, Y. X., Jan 1 2018, In : Nature Immunology. 19, 1, p. 6-7 2 p.

Research output: Contribution to journalShort survey

A Novel Anti-LILRB4 CAR-T Cell for the Treatment of Monocytic AML

John, S., Chen, H., Deng, M., Gui, X., Wu, G., Chen, W., Li, Z., Zhang, N., An, Z. & Zhang, C. C., Jan 1 2018, (Accepted/In press) In : Molecular Therapy.

Research output: Contribution to journalArticle

T-Cell Antigen Receptor
Acute Myeloid Leukemia
Immunoglobulins
Leukocytes
Myeloid Cells

A novel gain-of-function Nav1.7 mutation in a carbamazepine-responsive patient with adult-onset painful peripheral neuropathy

Adi, T., Estacion, M., Schulman, B. R., Vernino, S., Dib-Hajj, S. D. & Waxman, S. G., Jan 1 2018, In : Molecular pain. 14

Research output: Contribution to journalArticle

Carbamazepine
Peripheral Nervous System Diseases
Spinal Ganglia
Mutation
Neurons
3 Citations

A Novel Generalized Lipodystrophy-Associated Progeroid Syndrome Due to Recurrent Heterozygous LMNA p.T10I Mutation

Hussain, I., Patni, N., Ueda, M., Sorkina, E., Valerio, C. M., Cochran, E., Brown, R. J., Peeden, J., Tikhonovich, Y., Tiulpakov, A., Stender, S. R. S., Klouda, E., Tayeh, M. K., Innis, J. W., Meyer, A., Lal, P., Godoy-Matos, A. F., Teles, M. G., Adams-Huet, B., Rader, D. J. & 3 othersHegele, R. A., Oral, E. A. & Garg, A., Mar 1 2018, In : The Journal of clinical endocrinology and metabolism. 103, 3, p. 1005-1014 10 p.

Research output: Contribution to journalArticle

Congenital Generalized Lipodystrophy
Lamin Type A
Mutation
Transplants
Progeria

A novel inhibitor of pyruvate dehydrogenase kinase stimulates myocardial carbohydrate oxidation in diet-induced obesity

Wu, C. Y., Satapati, S., Gui, W., Max Wynn, R., Sharma, G., Lou, M., Qi, X., Burgess, S. C., Malloy, C., Khemtong, C., Dean Sherry, A., Chuang, D. T. & Merritt, M. E., Jan 1 2018, In : Journal of Biological Chemistry. 293, 25, p. 9604-9613 10 p.

Research output: Contribution to journalArticle

Obesity
Carbohydrates
Diet
pyruvate dehydrogenase (acetyl-transferring) kinase

A novel in vitro metric predicts in vivo efficacy of inhaled silver-based antimicrobials in a murine Pseudomonas aeruginosa pneumonia model

Shah, P. N., Shah, K. N., Smolen, J. A., Tagaev, J. A., Torrealba, J., Zhou, L., Zhang, S., Zhang, F., Wagers, P. O., Panzner, M. J., Youngs, W. J., Wooley, K. L. & Cannon, C. L., Dec 1 2018, In : Scientific Reports. 8, 1, 6376.

Research output: Contribution to journalArticle

Silver
Pseudomonas aeruginosa
Pneumonia
Pharmaceutical Preparations
Libraries