Toward a very brief quality of life enjoyment and Satisfaction Questionnaire

A. John Rush, Charles C. South, Manish K. Jha, Bruce D. Grannemann, Madhukar H. Trivedi

Research output: Contribution to journalArticle

Abstract

Objective: To develop and evaluate a new brief self-report measure of satisfaction/quality of life in depressed outpatients. Methods: Using the Quality of Life Enjoyment and Satisfaction Questionnaire Short-Form (Q-LES-Q-SF) self-report from Step-1 (n = 2181) of the STAR*D trial, items were selected based on their magnitude of change with treatment and correlation with 16-item Quick Inventory of Depressive Symptomatology Self-Report (QIDS-SR16). Psychometric analyses were conducted. Replication of scale performance was assessed with STAR*D Step-2 data (n = 250). Results: The 7 items selected (“Mini-Q-LES-Q”) rated satisfaction with work, household activities, social and family relations, leisure time activities, daily function and sense of well-being in the past week. This uni-dimensional scale captured 83–94% variance in Q-LES-Q-SF and had acceptable Item Response and Classical Test Theory characteristics. Baseline to exit percent changes in the Mini-Q-LES-Q and the QIDS-SR16 were significantly, modestly related (r = -0.552) (Step-1) and replicated (r = -0.562) (Step-2). The Mini-Q-LES-Q detected the expected improvement in satisfaction/quality of life in acute treatment, yet also identified residual deficits expected in many at acute-phase exit. Limitations: Population norms are yet undefined. Concurrent validity with detailed, well-validated scales that assess the seven Quality of Life domains incorporated in the Mini-Q-LES-Q remains unestablished. Sensitivity to symptom changes induced by psychotherapy or somatic therapies or sensitive to the effects of therapies aimed at enhancing quality of life enjoyment and function is unknown. Conclusion: The 7-item Mini-Q-LES-Q self-report measure satisfaction/quality of life has acceptable psychometric properties, reflects change with depressive symptom reduction, and detects residual deficits in this key clinical outcome.

LanguageEnglish (US)
Pages87-95
Number of pages9
JournalJournal of Affective Disorders
Volume242
DOIs
StatePublished - Jan 1 2019

Fingerprint

Quality of Life
Self Report
Psychometrics
Family Relations
Job Satisfaction
Leisure Activities
Therapeutics
Psychotherapy
Surveys and Questionnaires
Outpatients
Depression
Equipment and Supplies
Population

Keywords

  • Depression
  • Function
  • Psychosocial outcomes
  • Quality of life
  • Recovery
  • Satisfaction
  • Self-report

ASJC Scopus subject areas

  • Clinical Psychology
  • Psychiatry and Mental health

Cite this

Toward a very brief quality of life enjoyment and Satisfaction Questionnaire. / Rush, A. John; South, Charles C.; Jha, Manish K.; Grannemann, Bruce D.; Trivedi, Madhukar H.

In: Journal of Affective Disorders, Vol. 242, 01.01.2019, p. 87-95.

Research output: Contribution to journalArticle

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AU - Trivedi, Madhukar H.

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AB - Objective: To develop and evaluate a new brief self-report measure of satisfaction/quality of life in depressed outpatients. Methods: Using the Quality of Life Enjoyment and Satisfaction Questionnaire Short-Form (Q-LES-Q-SF) self-report from Step-1 (n = 2181) of the STAR*D trial, items were selected based on their magnitude of change with treatment and correlation with 16-item Quick Inventory of Depressive Symptomatology Self-Report (QIDS-SR16). Psychometric analyses were conducted. Replication of scale performance was assessed with STAR*D Step-2 data (n = 250). Results: The 7 items selected (“Mini-Q-LES-Q”) rated satisfaction with work, household activities, social and family relations, leisure time activities, daily function and sense of well-being in the past week. This uni-dimensional scale captured 83–94% variance in Q-LES-Q-SF and had acceptable Item Response and Classical Test Theory characteristics. Baseline to exit percent changes in the Mini-Q-LES-Q and the QIDS-SR16 were significantly, modestly related (r = -0.552) (Step-1) and replicated (r = -0.562) (Step-2). The Mini-Q-LES-Q detected the expected improvement in satisfaction/quality of life in acute treatment, yet also identified residual deficits expected in many at acute-phase exit. Limitations: Population norms are yet undefined. Concurrent validity with detailed, well-validated scales that assess the seven Quality of Life domains incorporated in the Mini-Q-LES-Q remains unestablished. Sensitivity to symptom changes induced by psychotherapy or somatic therapies or sensitive to the effects of therapies aimed at enhancing quality of life enjoyment and function is unknown. Conclusion: The 7-item Mini-Q-LES-Q self-report measure satisfaction/quality of life has acceptable psychometric properties, reflects change with depressive symptom reduction, and detects residual deficits in this key clinical outcome.

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